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  1. Tigecycline pharmacokinetics in critically ill patients on renal replacement therapy: possible warnings and potential perspectives for the research agenda

    … warnings and potential perspectives for the research agenda … MIR & AIC Copyright ©2020 The Author(s)

    10/02/2021 - 10:05

  2. Fluid resuscitation in human sepsis: Time to rewrite history?

    … on current experimental and clinical evidence. The research agenda should focus on the development of hyperdynamic …

    10/02/2021 - 10:10

  3. Assessment of renal hemodynamic toxicity of fluid challenge with 0.9% NaCl compared to balanced crystalloid (PlasmaLyte^®) in a rat model with severe sepsis

    … of renal hemodynamic toxicity of fluid challenge with 0.9% NaCl compared to balanced crystalloid (PlasmaLyte^®) in … or septic shock. Compared to balanced crystalloids, 0.9% sodium chloride (0.9% NaCl) induces hyperchloremia and metabolic acidosis and …

    10/02/2021 - 10:11

  4. Sodium lactate improves renal microvascular thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an experimental randomized open label controlled study

    … thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an … 11.2% (SL group); an isotonic control group received 0.9% NaCl (NC group); a hypertonic control group, with the …

    10/02/2021 - 10:09

  5. Qu'est-ce que la réanimation ? - 09 - Éthique et fin de vie

    Qu'est-ce que la réanimation ? - 09 - Éthique et fin de vie …

  6. Qu'est-ce que la réanimation ? - 09 - Ethique et fin de vie

    Qu'est-ce que la réanimation ? - 09 - Ethique et fin de vie Auteur(s) …

  7. Effects of chloride content of intravenous crystalloid solutions in critically ill adult patients: a meta-analysis with trial sequential analysis of randomized trials

    … solutions was associated with longer RRT-free days (SMD 0.09, 95% CI 0.06–0.12, p  < 0.001), less risk of …

    10/02/2021 - 10:08

  8. Impact of chloride and strong ion difference on ICU and hospital mortality in a mixed intensive care population

    … mortality in the ICU (odds ratio vs. normochloremia 1.81; 95 % CI 1.32–2.50; p  < 0.001) and the hospital (odds ratio 1.49; 95 % CI 1.14–1.96; p  = 0.003). Hyperchloremia and low …

    10/02/2021 - 10:12

  9. Respiratory mechanics and gas exchanges in the early course of COVID-19 ARDS: a hypothesis-generating study

    … mechanics and gas exchanges in the early course of COVID-19 ARDS: a hypothesis-generating study … and biological characteristics Methods Between March 22 and March 30, 2020 respiratory mechanics, gas exchanges, circulating …

    10/02/2021 - 10:05

  10. Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy

    … resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy … Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear of an imminent saturation of available ICU beds …

    10/02/2021 - 10:05